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Ectopic Expression of Fas Ligand on Cardiomyocytes Renders Cardiac Allografts Resistant to CD4(+) T-cell Mediated Rejection
Fas Ligand limits inflammatory injury and permits allograft survival by inducing apoptosis of Fas-bearing lymphocytes. Previous studies have shown that the CD4(+) T-cell is both sufficient and required for murine cardiac allograft rejection. Here, utilizing a transgenic mouse that over-expresses Fas...
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| Publicado no: | Cell Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298462/ https://ncbi.nlm.nih.gov/pubmed/25497973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2014.11.007 |
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