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CD4 T cell–mediated cardiac allograft rejection requires donor but not host MHC class II

Numerous studies indicate that CD4 T cells are required for acute cardiac allograft rejection. However, the precise role for CD4 T cells in this response has remained ambiguous owing to the multipotential properties of this T-cell subpopulation. In the current study, we demonstrate the capacity of C...

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Autors principals: Pietra, Biagio A., Wiseman, Alex, Bolwerk, Amy, Rizeq, Mona, Gill, Ronald G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC314344/
https://ncbi.nlm.nih.gov/pubmed/11032860
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