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IGF Binding Protein-4 is Required for the Growth Effects of Glucagon-Like Peptide-2 in Murine Intestine

Glucagon-like peptide-2 (GLP-2) is an enteroendocrine hormone that stimulates the growth of the intestinal epithelium. We have previously demonstrated that GLP-2 exerts its intestinotropic effect through an indirect mechanism that requires both IGF-1 and the intestinal epithelial IGF-1 receptor. How...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Austin, Kaori, Imam, Nuvair A., Pintar, John E., Brubaker, Patricia L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298331/
https://ncbi.nlm.nih.gov/pubmed/25514089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1829
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