Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2

Altered epidermal differentiation characterizes numerous skin diseases affecting >25% of the human population. Here we identified Fra-2/AP-1 as a key regulator of terminal epidermal differentiation. Epithelial-restricted, ectopic expression of Fra-2 induced expression of epidermal differentiation...

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Publicat a:Genes Dev
Autors principals: Wurm, Stefanie, Zhang, Jisheng, Guinea-Viniegra, Juan, García, Fernando, Muñoz, Javier, Bakiri, Latifa, Ezhkova, Elena, Wagner, Erwin F.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298134/
https://ncbi.nlm.nih.gov/pubmed/25547114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.249748.114
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