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Metabolism of [(14)C]Cefaclor, a Cephalosporin Antibiotic, in Three Species of Laboratory Animals

The metabolic fate of the orally effective cephalosporin antibiotic cefaclor (Lilly 99638) has been studied in rats, mice, and dogs. Cefaclor is efficiently absorbed from the gastrointestinal tract as the intact antibiotic. In rats and mice, cefaclor, for the most part, escapes metabolism in the bod...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Sullivan, Hugh R., Due, Susan L., Kau, Donald L. K., Quay, John F., Miller, Warren M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1976
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.4.630
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