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Metabolism of [(14)C]Cefaclor, a Cephalosporin Antibiotic, in Three Species of Laboratory Animals

The metabolic fate of the orally effective cephalosporin antibiotic cefaclor (Lilly 99638) has been studied in rats, mice, and dogs. Cefaclor is efficiently absorbed from the gastrointestinal tract as the intact antibiotic. In rats and mice, cefaclor, for the most part, escapes metabolism in the bod...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Sullivan, Hugh R., Due, Susan L., Kau, Donald L. K., Quay, John F., Miller, Warren M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1976
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/984800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.10.4.630
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