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Ion Selectivity in the Selectivity Filters of Acid-Sensing Ion Channels

Sodium-selective acid sensing ion channels (ASICs), which belong to the epithelial sodium channel (ENaC) superfamily, are key players in many physiological processes (e.g. nociception, mechanosensation, cognition, and memory) and are potential therapeutic targets. Central to the ASIC's function...

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Publicat a:Sci Rep
Autors principals: Dudev, Todor, Lim, Carmay
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297968/
https://ncbi.nlm.nih.gov/pubmed/25597624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07864
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