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Improving power for robust trans-ethnic meta-analysis of rare and low-frequency variants with a partitioning approach
While genome-wide association studies have discovered numerous bona fide variants that are associated with common diseases and complex traits; these variants tend to be common in the population and explain only a small proportion of the phenotype variance. The search for the missing heritability has...
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| Pubblicato in: | Eur J Hum Genet |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297906/ https://ncbi.nlm.nih.gov/pubmed/24801758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.78 |
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