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Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma
Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare (<1%) and low-frequency (1–5%) variants using the Illumina HumanExome BeadChip array in 4,794 asthma cases, 4,707 non-asthmatic controls and...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4309441/ https://ncbi.nlm.nih.gov/pubmed/25591454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6965 |
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