Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Common variants at many loci have been robustly associated with asthma but explain little of the overall genetic risk. Here we investigate the role of rare (<1%) and low-frequency (1–5%) variants using the Illumina HumanExome BeadChip array in 4,794 asthma cases, 4,707 non-asthmatic controls and...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Autores principales: Igartua, Catherine, Myers, Rachel A., Mathias, Rasika A., Pino-Yanes, Maria, Eng, Celeste, Graves, Penelope E., Levin, Albert M., Del-Rio-Navarro, Blanca E., Jackson, Daniel J., Livne, Oren E., Rafaels, Nicholas, Edlund, Christopher K., Yang, James J., Huntsman, Scott, Salam, Muhammad T., Romieu, Isabelle, Mourad, Raphael, Gern, James E., Lemanske, Robert F., Wyss, Annah, Hoppin, Jane A., Barnes, Kathleen C., Burchard, Esteban G., Gauderman, W. James, Martinez, Fernando D., Raby, Benjamin A., Weiss, Scott T., Williams, L. Keoki, London, Stephanie J., Gilliland, Frank D., Nicolae, Dan L., Ober, Carole
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309441/
https://ncbi.nlm.nih.gov/pubmed/25591454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6965
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares