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Improving power for robust trans-ethnic meta-analysis of rare and low-frequency variants with a partitioning approach

While genome-wide association studies have discovered numerous bona fide variants that are associated with common diseases and complex traits; these variants tend to be common in the population and explain only a small proportion of the phenotype variance. The search for the missing heritability has...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Zakharov, Sergii, Wang, Xu, Liu, Jianjun, Teo, Yik-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297906/
https://ncbi.nlm.nih.gov/pubmed/24801758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.78
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