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SHOX2 Overexpression Favors Differentiation of Embryonic Stem Cells into Cardiac Pacemaker Cells, Improving Biological Pacing Ability

When pluripotency factors are removed, embryonic stem cells (ESCs) undergo spontaneous differentiation, which, among other lineages, also gives rise to cardiac sublineages, including chamber cardiomyocytes and pacemaker cells. Such heterogeneity complicates the use of ESC-derived heart cells in ther...

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書目詳細資料
發表在:Stem Cell Reports
Main Authors: Ionta, Vittoria, Liang, Wenbin, Kim, Elizabeth H., Rafie, Reza, Giacomello, Alessandro, Marbán, Eduardo, Cho, Hee Cheol
格式: Artigo
語言:Inglês
出版: Elsevier 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297875/
https://ncbi.nlm.nih.gov/pubmed/25533636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.11.004
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