Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts. Reprogramming of EpiSCs to embryonic stem cell (ESC)-like cells (rESCs) may occur in response to LIF-STAT3 signaling; however, low reprog...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Murayama, Hideyuki, Masaki, Hideki, Sato, Hideyuki, Hayama, Tomonari, Yamaguchi, Tomoyuki, Nakauchi, Hiromitsu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297867/
https://ncbi.nlm.nih.gov/pubmed/25556568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.12.003
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