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Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin
Epiblast stem cells (EpiSCs) in mice and rats are primed pluripotent stem cells (PSCs). They barely contribute to chimeric embryos when injected into blastocysts. Reprogramming of EpiSCs to embryonic stem cell (ESC)-like cells (rESCs) may occur in response to LIF-STAT3 signaling; however, low reprog...
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| Publicado no: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297867/ https://ncbi.nlm.nih.gov/pubmed/25556568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.12.003 |
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