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G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets.

Using subtype-specific antisera, we were able to identify the recently described alpha subunits of G12 and G13 in platelet membranes as 43-kDa proteins. Activation of the thromboxane A2 and the thrombin receptors in platelet membranes led to increased incorporation of the photoreactive GTP analogue...

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Main Authors: Offermanns, S, Laugwitz, K L, Spicher, K, Schultz, G
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC42977/
https://ncbi.nlm.nih.gov/pubmed/8290554
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