Arsenic exposure is associated with DNA hypermethylation of the tumor suppressor gene p16

BACKGROUND: Occupational and environmental exposure to inorganic arsenic leads to development of cancer and represents a significant health hazard in more than 70 countries. The underlying mechanism for arsenic-induced carcinogenesis remains unclear. Laboratory studies suggest that arsenic is a poor...

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Detalhes bibliográficos
Publicado no:J Occup Med Toxicol
Main Authors: Lu, Guangming, Xu, Huiwen, Chang, De, Wu, Zhenglai, Yao, Xiaoyuan, Zhang, Shiying, Li, Zhenlong, Bai, Jieben, Cai, Qing, Zhang, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297462/
https://ncbi.nlm.nih.gov/pubmed/25598836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12995-014-0042-5
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