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Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer

Arsenic, though a poor mutagen, is an accepted environmental carcinogen. Perturbation of DNA methylation pattern leading to aberrant gene expression has been hypothesized as the mechanism for arsenic induced carcinogenesis. We had earlier demonstrated the hypermethylation of promoter region of p53 a...

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Detalhes bibliográficos
Main Authors: Chanda, Sarmishtha, Dasgupta, Uma B, Mazumder, Debendranath Guha, Saha, Jayita, Gupta, Bhaskar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825097/
https://ncbi.nlm.nih.gov/pubmed/24255851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-557
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