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Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer

Arsenic, though a poor mutagen, is an accepted environmental carcinogen. Perturbation of DNA methylation pattern leading to aberrant gene expression has been hypothesized as the mechanism for arsenic induced carcinogenesis. We had earlier demonstrated the hypermethylation of promoter region of p53 a...

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Autors principals: Chanda, Sarmishtha, Dasgupta, Uma B, Mazumder, Debendranath Guha, Saha, Jayita, Gupta, Bhaskar
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825097/
https://ncbi.nlm.nih.gov/pubmed/24255851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-557
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