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Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors
Arsenic trioxide (As(2)O(3)) exhibits potent antineoplastic effects and is used extensively in clinical oncology for the treatment of a subset of patients with acute myeloid leukemia (AML). Although As(2)O(3) is known to regulate activation of several signaling cascades, the key events, accounting f...
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| Publicado en: | Mol Cancer Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297272/ https://ncbi.nlm.nih.gov/pubmed/25344585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0665-T |
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