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Cathepsin G deficiency reduces peri-aortic calcium chloride injury-induced abdominal aortic aneurysms in mice

OBJECTIVE: Cathepsin G (CatG) is a serine protease that mediates angiotensin-I (Ang-I) to angiotensin-II (Ang-II) conversion and is highly expressed in human abdominal aortic aneurysms (AAAs). However, it remains untested whether this protease participates in the pathogenesis of AAA. METHODS AND RES...

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Publicat a:J Vasc Surg
Autors principals: Wang, Jing, Sukhova, Galina K., Liu, Jian, Ozaki, Keith, Lesner, Adam, Libby, Peter, Kovanen, Petri T., Shi, Guo-Ping
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297267/
https://ncbi.nlm.nih.gov/pubmed/25037606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2014.06.004
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