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Combined CDKN1A/TP53 mutation in bladder cancer is a therapeutic target

Invasive bladder cancer has high morbidity and nearly uniform mortality when metastatic, with no therapeutic improvement in many years. Although chemotherapy combined with Chk1 inhibition has been investigated in several cancer types in which TP53 mutation is seen, this combination treatment approac...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Liu, Yang, Kwiatkowski, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297264/
https://ncbi.nlm.nih.gov/pubmed/25349305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0622-T
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