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Pharmacological profiling of kinase dependency in cell lines across triple-negative breast cancer subtypes

Triple-negative breast cancers (TNBC), negative for estrogen receptor, progesterone receptor, and Her2 amplification, are resistant to standard targeted therapies and exhibit a poor prognosis. Furthermore, they are highly heterogeneous with respect to genomic alterations, and common therapeutic targ...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Fink, Lauren S., Beatty, Alexander, Devarajan, Karthik, Peri, Suraj, Peterson, Jeffrey R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297247/
https://ncbi.nlm.nih.gov/pubmed/25344583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0529
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