Role of Protein Farnesylation in Burn-Induced Metabolic Derangements and Insulin Resistance in Mouse Skeletal Muscle

OBJECTIVE: Metabolic derangements, including insulin resistance and hyperlactatemia, are a major complication of major trauma (e.g., burn injury) and affect the prognosis of burn patients. Protein farnesylation, a posttranslational lipid modification of cysteine residues, has been emerging as a pote...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakazawa, Harumasa, Yamada, Marina, Tanaka, Tomokazu, Kramer, Joshua, Yu, Yong-Ming, Fischman, Alan J., Martyn, J. A. Jeevendra, Tompkins, Ronald G., Kaneki, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296934/
https://ncbi.nlm.nih.gov/pubmed/25594415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116633
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