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Historical Controls for Metastatic Pancreatic Cancer: Benchmarks for Planning and Analyzing Single Arm Phase II Trials

We compiled and analyzed a database of cooperative group trials in advanced pancreatic cancer, to develop historical benchmarks for overall survival (OS) and progression free survival (PFS). Such benchmarks are essential for evaluating new therapies in a single arm setting. The analysis included pat...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Philip, Philip A., Chansky, Kari, LeBlanc, Michael, Rubinstein, Lawrence, Seymour, Lesley, Ivy, S. Percy, Alberts, Steven R., Catalano, Paul J., Crowley, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296727/
https://ncbi.nlm.nih.gov/pubmed/24914040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2024
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