Senescence marker protein-30/gluconolactonase deficiency exacerbates diabetic nephropathy through tubular injury in a mouse model of type 1 diabetes

AIMS/INTRODUCTION: Senescence marker protein-30 (SMP30) is abundantly expressed in renal proximal tubule cells, but its expression decreases with age. Previous studies have shown that reduced SMP30 expression could contribute to aging-associated deterioration of cellular function and tissue injury....

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Detalhes bibliográficos
Publicado no:J Diabetes Investig
Main Authors: Okada, Hiroshi, Senmaru, Takafumi, Fukui, Michiaki, Kondo, Yoshitaka, Ishigami, Akihito, Maruyama, Naoki, Obayashi, Hiroshi, Yamazaki, Masahiro, Nakamura, Naoto, Hasegawa, Goji
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296701/
https://ncbi.nlm.nih.gov/pubmed/25621131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12252
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