Senescence marker protein 30 functions as gluconolactonase in l-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy

We originally identified senescence marker protein 30 (SMP30) as a distinctive protein whose expression decreases in an androgen-independent manner with aging. Here, we report its sequence homology found in two kinds of bacterial gluconolactonases (GNLs) by using the blast search. Then, through a bi...

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Detalhes bibliográficos
Main Authors: Kondo, Yoshitaka, Inai, Yoko, Sato, Yasunori, Handa, Setsuko, Kubo, Sachiho, Shimokado, Kentaro, Goto, Sataro, Nishikimi, Morimitsu, Maruyama, Naoki, Ishigami, Akihito
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458640/
https://ncbi.nlm.nih.gov/pubmed/16585534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511225103
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