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BDNF and Huntingtin protein modifications by Manganese: Implications for striatal medium spiny neuron pathology in manganese neurotoxicity

High levels of manganese (Mn) exposure decreases striatal medium spiny neuron (MSN) dendritic length and spine density, but the mechanism(s) are not known. The Huntingtin (HTT) gene has been functionally linked to cortical brain-derived neurotrophic factor (BDNF) support of striatal MSNs via phospho...

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Podrobná bibliografie
Vydáno v:J Neurochem
Hlavní autoři: Stansfield, Kirstie H., Bichell, Terry Jo, Bowman, Aaron B., Guilarte, Tomás R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296578/
https://ncbi.nlm.nih.gov/pubmed/25099302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12926
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