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A nonsense mutation in the HOXD13 gene underlies synpolydactyly with incomplete penetrance

Synpolydactyly 1 (SPD1; OMIM 186000), also known as type II syndactyly, is a dominantly inherited limb malformation that is characterized by an increased number of digits. SPD1 is most commonly caused by polyalanine repeat expansions in the coding region of the HOXD13 gene, which are believed to sho...

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Dades bibliogràfiques
Publicat a:J Hum Genet
Autors principals: Kurban, Mazen, Wajid, Muhammad, Petukhova, Lynn, Shimomura, Yutaka, Christiano, Angela M
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296310/
https://ncbi.nlm.nih.gov/pubmed/21814222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2011.84
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