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Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins

Glycosaminoglycans (GAGs) interact with many proteins to regulate processes such as hemostasis, cell adhesion, growth and differentiation and viral infection. Yet, majority of these interactions remain poorly understood at a molecular level. A major reason for this state is the phenomenal structural...

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Détails bibliographiques
Publié dans:Glycobiology
Auteurs principaux: Sankaranarayanan, Nehru Viji, Desai, Umesh R
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296175/
https://ncbi.nlm.nih.gov/pubmed/25049239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu077
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