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A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules

Glycosaminoglycans (GAGs) are key natural biopolymers that exhibit a range of biological functions including growth and differentiation. Despite this multiplicity of function, natural GAG sequences have not yielded drugs because of problems of heterogeneity and synthesis. Recently, several homogenou...

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מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Nagarajan, Balaji, Sankaranarayanan, Nehru Viji, Patel, Bhaumik B., Desai, Umesh R.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300208/
https://ncbi.nlm.nih.gov/pubmed/28182755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171619
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