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Designing ‘High-Affinity, High-Specificity’ Glycosaminoglycan Sequences Through Computerized Modeling

The prediction of high-affinity and/or high-specificity protein–glycosaminoglycan (GAG) interactions is an inherently difficult task, due to several factors including the shallow nature of the typical GAG binding site and the inherent size, flexibility, diversity and polydisperse nature of the GAG m...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Sankaranarayanan, Nehru Viji, Sarkar, Aurijit, Desai, Umesh R., Mosier, Philip D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452111/
https://ncbi.nlm.nih.gov/pubmed/25325961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-1714-3_24
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