Clinical Pharmacokinetics of Sisomicin: Dosage Schedules in Renal-Impaired Patients

The pharmacokinetics of intravenously administered sisomicin were studied in 33 patients with normal renal function and different degrees of renal impairment. In all patients, the serum disappearance of sisomicin, once distribution equilibrium had been achieved, followed first-order kinetics and per...

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Dettagli Bibliografici

Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Pechère, Jean-Claude, Pechère, Marie-Madeleine, Dugal, Robert
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1976
Soggetti:	Pharmacology and Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429617/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/986124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.9.5.761
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