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Cosi2: an efficient simulator of exact and approximate coalescent with selection

Motivation: Efficient simulation of population genetic samples under a given demographic model is a prerequisite for many analyses. Coalescent theory provides an efficient framework for such simulations, but simulating longer regions and higher recombination rates remains challenging. Simulators bas...

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Publicat a:Bioinformatics
Autors principals: Shlyakhter, Ilya, Sabeti, Pardis C., Schaffner, Stephen F.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4296154/
https://ncbi.nlm.nih.gov/pubmed/25150247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu562
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