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Discoal: flexible coalescent simulations with selection

Summary: Here we describe discoal, a coalescent simulator able to generate population samples that include selective sweeps in a feature-rich, flexible manner. discoal can perform simulations conditioning on the fixation of an allele due to drift or either hard or soft sweeps—even those occurring a...

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Publicat a:Bioinformatics
Autors principals: Kern, Andrew D., Schrider, Daniel R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167068/
https://ncbi.nlm.nih.gov/pubmed/27559153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw556
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