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scrm: efficiently simulating long sequences using the approximated coalescent with recombination

Motivation: Coalescent-based simulation software for genomic sequences allows the efficient in silico generation of short- and medium-sized genetic sequences. However, the simulation of genome-size datasets as produced by next-generation sequencing is currently only possible using fairly crude appro...

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Pubblicato in:Bioinformatics
Autori principali: Staab, Paul R., Zhu, Sha, Metzler, Dirk, Lunter, Gerton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426833/
https://ncbi.nlm.nih.gov/pubmed/25596205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu861
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