Telotristat Etiprate, a Novel Serotonin Synthesis Inhibitor, in Patients with Carcinoid Syndrome and Diarrhea Not Adequately Controlled by Octreotide

Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We assessed the safety and efficacy of telotristat etiprate, an oral serotonin synthesis inhibitor, in patients with diarrhea associated with carcinoid syndrome. In this prospective...

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Publicat a:Endocr Relat Cancer
Autors principals: Kulke, Matthew H., O’Dorisio, Thomas, Phan, Alexandria, Bergsland, Emily, Law, Linda, Banks, Phillip, Freiman, Joel, Frazier, Kenny, Jackson, Jessica, Yao, James C., Kvols, Larry, Lapuerta, Pablo, Zambrowicz, Brian, Fleming, Douglas, Sands, Arthur
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295770/
https://ncbi.nlm.nih.gov/pubmed/25012985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0173
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