Telotristat Etiprate, a Novel Serotonin Synthesis Inhibitor, in Patients with Carcinoid Syndrome and Diarrhea Not Adequately Controlled by Octreotide

Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We assessed the safety and efficacy of telotristat etiprate, an oral serotonin synthesis inhibitor, in patients with diarrhea associated with carcinoid syndrome. In this prospective...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Kulke, Matthew H., O’Dorisio, Thomas, Phan, Alexandria, Bergsland, Emily, Law, Linda, Banks, Phillip, Freiman, Joel, Frazier, Kenny, Jackson, Jessica, Yao, James C., Kvols, Larry, Lapuerta, Pablo, Zambrowicz, Brian, Fleming, Douglas, Sands, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295770/
https://ncbi.nlm.nih.gov/pubmed/25012985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0173
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