Telotristat Etiprate, a Novel Serotonin Synthesis Inhibitor, in Patients with Carcinoid Syndrome and Diarrhea Not Adequately Controlled by Octreotide

Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We assessed the safety and efficacy of telotristat etiprate, an oral serotonin synthesis inhibitor, in patients with diarrhea associated with carcinoid syndrome. In this prospective...

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Publicado en:Endocr Relat Cancer
Autores principales: Kulke, Matthew H., O’Dorisio, Thomas, Phan, Alexandria, Bergsland, Emily, Law, Linda, Banks, Phillip, Freiman, Joel, Frazier, Kenny, Jackson, Jessica, Yao, James C., Kvols, Larry, Lapuerta, Pablo, Zambrowicz, Brian, Fleming, Douglas, Sands, Arthur
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295770/
https://ncbi.nlm.nih.gov/pubmed/25012985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0173
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