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Sorting out functions of sirtuins in cancer
The sirtuins (SIRT 1-7) comprise a family of NAD(+) dependent protein modifying enzymes with activities in lysine deacetylation, ADP-ribosylation, and/or deacylation. These enzymes are involved in the cell’s stress response systems and in regulating gene expression, DNA damage repair, metabolism and...
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| Published in: | Oncogene |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4295628/ https://ncbi.nlm.nih.gov/pubmed/23604120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.120 |
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