Loss of BRMS1 Promotes a Mesenchymal Phenotype through NF-κB-Dependent Regulation of Twist1

Breast cancer metastasis suppressor 1 (BRMS1) is downregulated in non-small cell lung cancer (NSCLC), and its reduction correlates with disease progression. Herein, we investigate the mechanisms through which loss of the BRMS1 gene contributes to epithelial-to-mesenchymal transition (EMT). Using a s...

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Publicado no:Mol Cell Biol
Main Authors: Liu, Yuan, Mayo, Marty W., Xiao, Aizhen, Hall, Emily H., Amin, Elianna B., Kadota, Kyuichi, Adusumilli, Prasad S., Jones, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4295387/
https://ncbi.nlm.nih.gov/pubmed/25368381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00869-14
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