Inhibition of Breast Cancer Metastasis Suppressor 1 Promotes a Mesenchymal Phenotype in Lung Epithelial Cells That Express Oncogenic K-Ras(V12) and Loss of p53

Expression of the breast cancer metastasis suppressor 1 (BRMS1) protein is dramatically reduced in non-small cell lung cancer (NSCLC) cells and in primary human tumors. Although BRMS1 is a known suppressor of metastasis, the mechanisms through which BRMS1 functions to regulate cell migration and inv...

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Detalhes bibliográficos
Main Authors: Hall, Emily H., Liu, Yuan, Xiao, Aizhen, Shock, Lisa, Brautigan, David L., Mayo, Marty W., Adusumilli, Prasad S., Jones, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999110/
https://ncbi.nlm.nih.gov/pubmed/24763730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095869
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