UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in European and African American smokers

BACKGROUND: Identifying sources of variation in the nicotine and nitrosamine metabolic inactivation pathways is important to understanding the relationship between smoking and cancer risk. Numerous UGT1A and UGT2B enzymes are implicated in nicotine and nitrosamine metabolism in vitro; however, littl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Epidemiol Biomarkers Prev
Autori principali: Wassenaar, Catherine A., Conti, David V., Das, Soma, Chen, Peixian, Cook, Edwin H., Ratain, Mark J., Benowitz, Neal L., Tyndale, Rachel F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294984/
https://ncbi.nlm.nih.gov/pubmed/25277794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-14-0804
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi