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MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways
Oncogenic RAS promotes production of reactive oxygen species (ROS), which mediate pro-malignant signaling but can also trigger DNA damage-induced tumor suppression. Thus RAS-driven tumor cells require redox-protective mechanisms to mitigate the damaging aspects of ROS. Here we show that MutT Homolog...
Tallennettuna:
| Julkaisussa: | Oncogene |
|---|---|
| Päätekijät: | , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294948/ https://ncbi.nlm.nih.gov/pubmed/25023700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.195 |
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