UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement.

Many human skin tumors contain mutated p53 genes that probably result from UV exposure. To investigate the link between UV exposure and p53 gene mutation, we developed two methods to detect presumptive UV-specific p53 gene mutations in UV-exposed normal skin. The methods are based on mutant allele-s...

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Detalhes bibliográficos
Principais autores: Nakazawa, H, English, D, Randell, P L, Nakazawa, K, Martel, N, Armstrong, B K, Yamasaki, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42947/
https://ncbi.nlm.nih.gov/pubmed/8278394
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