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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.

Sunlight is a carcinogen to which everyone is exposed. Its UV component is the major epidemiologic risk factor for squamous cell carcinoma of the skin. Of the multiple steps in tumor progression, those that are sunlight-related would be revealed if they contained mutations specific to UV. In a serie...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Brash, D E, Rudolph, J A, Simon, J A, Lin, A, McKenna, G J, Baden, H P, Halperin, A J, Pontén, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946433/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10124
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