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Role of Glucose Metabolism and ATP in Maintaining PINK1 Levels during Parkin-mediated Mitochondrial Damage Responses

Mutations in several genes, including PINK1 and Parkin, are known to cause autosomal recessive cases of Parkinson disease in humans. These genes operate in the same pathway and play a crucial role in mitochondrial dynamics and maintenance. PINK1 is required to recruit Parkin to mitochondria and init...

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Vydáno v:J Biol Chem
Hlavní autoři: Lee, Schuyler, Zhang, Conggang, Liu, Xuedong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294517/
https://ncbi.nlm.nih.gov/pubmed/25404737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606798
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