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PINK1 Triggers Autocatalytic Activation of Parkin to Specify Cell Fate Decisions
BACKGROUND: The PINK1-Parkin pathway is known to play important roles in regulating mitochondria dynamics, motility, and quality control. Activation of this pathway can be triggered by a variety of cellular stressor signals that cause mitochondrial damage. How this pathway senses different levels of...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143385/ https://ncbi.nlm.nih.gov/pubmed/25088558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.07.014 |
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