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Error-prone Translesion Synthesis Past DNA-Peptide Cross-links Conjugated to the Major Groove of DNA via C5 of Thymidine

DNA-protein cross-links (DPCs) are exceptionally bulky, structurally diverse DNA adducts formed in cells upon exposure to endogenous and exogenous bis-electrophiles, reactive oxygen species, and ionizing radiation. If not repaired, DPCs can induce toxicity and mutations. It has been proposed that th...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Wickramaratne, Susith, Boldry, Emily J., Buehler, Charles, Wang, Yen-Chih, Distefano, Mark D., Tretyakova, Natalia Y.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294500/
https://ncbi.nlm.nih.gov/pubmed/25391658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613638
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