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Synthesis of Site-Specific DNA–Protein Conjugates and Their Effects on DNA Replication

[Image: see text] DNA–protein cross-links (DPCs) are bulky, helix-distorting DNA lesions that form in the genome upon exposure to common antitumor drugs, environmental/occupational toxins, ionizing radiation, and endogenous free-radical-generating systems. As a result of their considerable size and...

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Detalhes bibliográficos
Main Authors: Yeo, Jung Eun, Wickramaratne, Susith, Khatwani, Santoshkumar, Wang, Yen-Chih, Vervacke, Jeffrey, Distefano, Mark D., Tretyakova, Natalia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136702/
https://ncbi.nlm.nih.gov/pubmed/24918113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5001795
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