Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged mice

This study was to investigate the influence of age on the expression of organic cation transporters (OCTs) that belong to the SLC22 family in brain microvessels (BMVs) and its implications for 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in mice. Here, we showed...

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Publicado en:J Cereb Blood Flow Metab
Autores principales: Wu, Kuo-Chen, Lu, Ya-Hsuan, Peng, Yi-Hsuan, Tsai, Ting-Fen, Kao, Yu-Han, Yang, Hui-Ting, Lin, Chun-Jung
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294392/
https://ncbi.nlm.nih.gov/pubmed/25248837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.162
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